CFAP92

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFAP92 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP92-associated genes across cancer lineages are KRT32, SHISAL2B, and SCN2B. Each is linked with CFAP92 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP92-to-partner and partner-to-CFAP92 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT32 grouped by CFAP92-low versus CFAP92-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP92→partner) and Y-score (partner→CFAP92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaKRT32 →+0.007+4.285<.001.00331
BLOOD_MyelomaSHISAL2B →+0.031+3.906.001.00931
BLOOD_MyelomaSCN2B →+0.012+4.754<.001<.00131
BLOOD_MyelomaVWA3B →+0.020+4.285.007.00331
BLOOD_MyelomaOR14I1 →+0.284+3.906.004.00931
BLOOD_LeukemiaKRTAP12-3 →+0.124+5.539<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

KRT32 by CFAP92 expression — BLOOD_Myeloma

Box plot of KRT32 in CFAP92-low vs CFAP92-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration