CFAP70

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CFAP70 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CFAP70 data layer compared with 20 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CFAP70 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CFAP70 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

KIRP, UCEC, and BLCA are the cancer types where CFAP70 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPOSMedianII,III,IV0.1480.771<.00118view →
UCECDFSMedianAll0.9110.608.01514view →
BLCAOSMedianIV0.8290.238.0178view →
SKCMOSMedianIII,IV0.4500.854.0037view →
UVMOSMedianAll0.3150.711.0493view →
STADOSMedianAll0.1230.540.0353view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CFAP70–KIRP (OS)

Kaplan–Meier survival curve for CFAP70 mutant vs wild-type samples in KIRP.

Open the KIRP breakdown →

Exploration