CFAP65

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFAP65 mutation is significantly associated with the RNA expression of many other genes, with 518 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP65-associated genes across cancer lineages are HINT1, NDUFA6, and GAGE12F. Each is linked with CFAP65 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP65-to-partner and partner-to-CFAP65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HINT1 grouped by CFAP65-low versus CFAP65-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP65→partner) and Y-score (partner→CFAP65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEHINT1 →+0.333+2.584.005.00233
LARGE_INTESTINENDUFA6 →+0.553+1.936.002.00532
SOFT_TISSUEGAGE12F →+0.557+2.372<.001.00232
SOFT_TISSUEYIPF1 →+0.479+2.592.005.00432
LARGE_INTESTINEDTWD1 →+0.475+2.000.006.00932
LARGE_INTESTINEC1QBP →+0.646+3.129<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 518 associations by consensus.

HINT1 by CFAP65 expression — LARGE_INTESTINE

Box plot of HINT1 in CFAP65-low vs CFAP65-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration