CFAP58-DT

Across TCGA pan-cancer cohorts, CFAP58-DT RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CFAP58-DT data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CFAP58-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CFAP58-DT expression acts as an unfavorable survival marker, although some lineages such as UVM and OV show a favorable association.

UVM, OV, and CHOL are the cancer types where CFAP58-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.769	0.389	<.001	109	view →
OV	DFS	Tertile	All	0.258	0.131	<.001	58	view →
CHOL	DFS	Tertile	II,III,IV	0.732	0.097	.001	50	view →
THYM	OS	Median	All	0.730	1.000	<.001	42	view →
LAML	DFS	Tertile	All	0.263	0.546	.003	36	view →
BLCA	DFS	Quartile	All	0.432	0.592	.007	28	view →
HNSC	DFS	Median	III,IV	0.247	0.445	.007	22	view →
GBM	OS	Tertile	All	0.325	0.629	.003	21	view →
STAD	DFS	Quartile	III,IV	0.323	0.721	.001	19	view →
TGCT	DFS	Tertile	All	0.938	0.729	.006	18	view →
UCEC	DFS	Median	All	0.492	0.782	.003	16	view →
ESCA	OS	Tertile	All	0.816	0.624	.012	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CFAP58-DT–UVM (DFS)

Open the UVM breakdown →