CFAP58-DT

Across TCGA pan-cancer cohorts, CFAP58-DT RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CFAP58-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CFAP58-DT RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CFAP58-DT is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRC, KICH, and UCEC are the cancer types where CFAP58-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CFAP58-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.523	<.001	11	view →
KICH	Male	II,III,IV	−0.787	<.001	10	view →
UCEC	All	All	−0.715	<.001	8	view →
HNSC	All	All	+0.571	<.001	7	view →
BRCA	All	II,III,IV	+0.484	<.001	6	view →
THCA	All	All	−0.186	.002	4	view →
LUSC	All	All	+0.443	.004	2	view →
PRAD	All	All	−0.210	.036	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CFAP58-DT–KIRC

Open the KIRC breakdown →