CFAP57

Across TCGA pan-cancer cohorts, CFAP57 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated CFAP57 data layer compared with 23 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CFAP57 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CFAP57 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

KIRC, UCEC, and BRCA are the cancer types where CFAP57 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.169	0.883	<.001	48	view →
UCEC	DFS	Median	All	1.000	0.621	.002	36	view →
BRCA	OS	Median	All	0.561	0.924	.002	24	view →
SKCM	DFS	Median	II,III,IV	0.805	0.552	.008	24	view →
BLCA	DFS	Median	III,IV	1.000	0.268	.024	10	view →
CESC	OS	Median	II,III,IV	0.118	0.555	.010	8	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CFAP57–KIRC (OS)

Open the KIRC breakdown →