Across TCGA patient cohorts, CFAP54 mutation is significantly associated with the RNA expression of many other genes, with 7,058 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP54-associated genes across cancer lineages are HMGN2, HMGN1, and MTHFD1. Each is linked with CFAP54 in more than 3 cancer types. Because this analysis shows association rather than direction, both CFAP54-to-partner and partner-to-CFAP54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP54→partner) and Y-score (partner→CFAP54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HMGN2 →	+0.553	+3.762	<.001	<.001	3	4
UCEC	HMGN1 →	+0.334	+1.885	.001	.001	3	4
UCEC	MTHFD1 →	+0.529	+2.506	<.001	<.001	3	4
LUAD	PIMREG →	+1.181	+3.906	<.001	<.001	3	4
LUAD	CEP85 →	+0.534	+3.483	<.001	.002	3	4
LUAD	KIF23 →	+1.044	+2.924	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,058 associations by consensus.

Exploration

CFAP54 survival (RNA) · tumor vs normal (RNA) · all CFAP54 data types