Across TCGA patient cohorts, CFAP54 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP54-associated genes across cancer lineages are ACVRL1, PCNA, and 4E-BP1. Each is linked with CFAP54 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP54-to-partner and partner-to-CFAP54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP54→partner) and Y-score (partner→CFAP54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ACVRL1 →	-0.136	-3.118	.030	.018	3	3
UCEC	PCNA →	+0.188	+1.280	<.001	.003	3	3
UCEC	4E-BP1 →	+0.342	+3.523	<.001	<.001	3	3
COAD	Caspase-7-cleavedD198 →	+1.149	+2.815	.008	.036	3	3
UCEC	FASN →	+0.275	+1.473	.007	.005	3	3
UCEC	TFRC →	+0.342	+1.415	.013	.040	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

CFAP54 survival (RNA) · tumor vs normal (RNA) · all CFAP54 data types