CFAP52

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CFAP52 mutation is significantly associated with the RNA expression of many other genes, with 4,279 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP52-associated genes across cancer lineages are RNU6-847P, DUTP3, and MIR4428. Each is linked with CFAP52 in more than 3 cancer types. Because this analysis shows association rather than direction, both CFAP52-to-partner and partner-to-CFAP52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-847P grouped by CFAP52-low versus CFAP52-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP52→partner) and Y-score (partner→CFAP52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNU6-847P →+0.242+8.055<.001.00734
LUADDUTP3 →+0.054+5.333<.001.00133
STADMIR4428 →+1.039+3.715.003.00633
SKCMRPS10-NUDT3 →+0.294+2.010<.001.00332
UCECIGKV1D-13 →+1.167+2.271.001.00132
LUSCRNA5SP411 →+0.999+4.733<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,279 associations by consensus.

RNU6-847P by CFAP52 expression — BRCA

Box plot of RNU6-847P in CFAP52-low vs CFAP52-high samples in BRCA.

Explore this box plot interactively →

Exploration