CFAP52

Across TCGA cell cohorts, CFAP52 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,398 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CFAP52-associated GO terms across cancer lineages are Negative regulation of MHC class II biosynthetic process, Response to indole-3-methanol, and Phospholipid biosynthetic process. Each is linked with CFAP52 in more than 6 cancer types. Because this analysis shows association rather than direction, both CFAP52-to-partner and partner-to-CFAP52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of MHC class II biosynthetic process grouped by CFAP52-low versus CFAP52-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP52→partner) and Y-score (partner→CFAP52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of MHC class II biosynthetic process →	+0.164	+0.179	.003	.001	3	7
BLOOD_Leukemia	Response to indole-3-methanol →	+0.129	+0.159	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.038	+0.246	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.099	-0.286	<.001	<.001	3	6
BREAST	Regulation of protein folding →	+0.078	+0.259	.002	.001	3	6
OVARY	Regulation of myoblast fusion →	+0.112	+0.290	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,398 associations by consensus.

Negative regulation of MHC class II biosynthetic process by CFAP52 expression — LARGE_INTESTINE

Explore this box plot interactively →