CFAP300

Across TCGA patient cohorts, CFAP300 mutation is significantly associated with the RNA expression of many other genes, with 993 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP300-associated genes across cancer lineages are TANGO2, KRT8P41, and MIR302A. Each is linked with CFAP300 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP300-to-partner and partner-to-CFAP300 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TANGO2 grouped by CFAP300-low versus CFAP300-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP300→partner) and Y-score (partner→CFAP300) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TANGO2 →	+0.653	+4.180	<.001	<.001	3	2
UCEC	KRT8P41 →	+0.264	+1.981	<.001	.008	3	2
LIHC	MIR302A →	+0.645	+5.878	<.001	.002	3	1
LIHC	MIR1271 →	+0.907	+5.758	<.001	.003	3	1
LIHC	RPL32P30 →	+0.200	+5.186	<.001	.007	3	1
SKCM	DHFRP3 →	+0.037	+2.943	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 993 associations by consensus.

TANGO2 by CFAP300 expression — UCEC

Explore this box plot interactively →