Across TCGA patient cohorts, CFAP299 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP299-associated genes across cancer lineages are JNK2, FoxM1, and MSH2. Each is linked with CFAP299 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP299-to-partner and partner-to-CFAP299 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP299→partner) and Y-score (partner→CFAP299) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.258	+3.009	.009	.019	3	2
UCEC	FoxM1 →	+0.283	+2.321	.029	.035	3	1
UCEC	MSH2 →	-0.426	-2.973	<.001	.035	3	1
UCEC	Notch1 →	+0.256	+2.321	<.001	.035	3	1
UCEC	Rictor_pT1135 →	-0.128	-2.321	.012	.035	3	1
UCEC	S6_pS240_S244 →	+0.563	+2.321	.005	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

CFAP299 survival (RNA) · tumor vs normal (RNA) · all CFAP299 data types