CFAP298

Across TCGA patient cohorts, CFAP298 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP298-associated genes across cancer lineages are p62 Lck ligand, BRCA2, and 4E-BP1. Each is linked with CFAP298 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP298-to-partner and partner-to-CFAP298 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by CFAP298-low versus CFAP298-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP298→partner) and Y-score (partner→CFAP298) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.465	+2.469	.001	.010	3	2
UCEC	BRCA2 →	-0.163	-2.574	.003	.010	3	2
UCEC	4E-BP1 →	+0.332	+3.169	.005	.018	3	2
UCEC	eEF2 →	+0.435	+2.807	.005	.003	3	1
UCEC	Gab2 →	+0.372	+2.115	.017	.019	3	1
UCEC	GAPDH →	+0.570	+2.807	.015	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

p62 Lck ligand by CFAP298 expression — UCEC

Explore this box plot interactively →