CFAP298-TCP10L

Across TCGA pan-cancer cohorts, CFAP298-TCP10L RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CFAP298-TCP10L’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CFAP298-TCP10L RNA is repressed in tumor relative to normal tissue. In most cancer types CFAP298-TCP10L is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, LIHC, and COAD are the cancer types where CFAP298-TCP10L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CFAP298-TCP10L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.721	<.001	10	view →
LIHC	Female	All	+0.211	<.001	6	view →
COAD	Male	II,III,IV	−0.178	.001	4	view →
BRCA	All	All	+0.157	.002	4	view →
THCA	All	All	−0.107	.017	4	view →
CHOL	All	All	+0.343	.010	2	view →
UCEC	All	III,IV	−0.321	.041	2	view →
LUSC	All	III,IV	−0.254	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CFAP298-TCP10L–KICH

Open the KICH breakdown →