CFAP157

Across TCGA patient cohorts, CFAP157 mutation is significantly associated with the RNA expression of many other genes, with 783 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP157-associated genes across cancer lineages are RNU6-666P, LYPLA1P1, and SNRPGP8. Each is linked with CFAP157 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP157-to-partner and partner-to-CFAP157 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-666P grouped by CFAP157-low versus CFAP157-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP157→partner) and Y-score (partner→CFAP157) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-666P →	+0.986	+6.734	<.001	<.001	3	2
COAD	LYPLA1P1 →	+0.428	+6.409	<.001	<.001	3	2
COAD	SNRPGP8 →	+0.286	+5.721	<.001	.001	3	2
COAD	RN7SL567P →	+0.521	+4.790	<.001	.006	3	2
UCEC	RN7SL470P →	+0.165	+1.916	.006	.007	3	2
UCEC	OR51A7 →	+0.089	+2.561	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 783 associations by consensus.

RNU6-666P by CFAP157 expression — COAD

Explore this box plot interactively →