CFAP157

Across TCGA pan-cancer cohorts, CFAP157 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CFAP157’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CFAP157 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CFAP157 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, THCA, and STAD are the cancer types where CFAP157 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CFAP157 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.333	<.001	11	view →
THCA	Male	III,IV	−0.690	<.001	11	view →
STAD	All	II,III,IV	+1.084	<.001	9	view →
KICH	Female	All	−0.531	<.001	9	view →
BLCA	All	All	+0.470	<.001	9	view →
LIHC	Male	II,III,IV	+0.436	<.001	9	view →
HNSC	Male	IV	+0.909	<.001	8	view →
KIRC	Male	II,III,IV	−0.312	<.001	8	view →
READ	All	All	+1.188	<.001	7	view →
LUAD	All	All	−0.831	<.001	7	view →
BRCA	All	III,IV	+0.728	<.001	6	view →
CHOL	All	All	+1.227	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CFAP157–COAD

Open the COAD breakdown →