CFAP157

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFAP157 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CFAP157-associated genes across cancer lineages are H2BC1, H2AC1, and UBQLN3. Each is linked with CFAP157 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP157-to-partner and partner-to-CFAP157 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2BC1 grouped by CFAP157-low versus CFAP157-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP157→partner) and Y-score (partner→CFAP157) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEH2BC1 →+0.325+4.977<.001.00231
SOFT_TISSUEH2AC1 →+0.145+4.977<.001.00231
SOFT_TISSUEUBQLN3 →+0.020+4.977<.001.00231
SOFT_TISSUEIFNA14 →+0.024+4.369<.001.00831
SOFT_TISSUEOR11H12 →+0.058+4.222<.001.00731
SOFT_TISSUECT45A9 →+0.987+4.635<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

H2BC1 by CFAP157 expression — SOFT_TISSUE

Box plot of H2BC1 in CFAP157-low vs CFAP157-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration