CETN2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CETN2 mutation is significantly associated with the RNA expression of many other genes, with 1,919 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CETN2-associated genes across cancer lineages are LINC02672, PGAP2, and COX15. Each is linked with CETN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CETN2-to-partner and partner-to-CETN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02672 grouped by CETN2-low versus CETN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CETN2→partner) and Y-score (partner→CETN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC02672 →+0.108+4.495<.001.00732
UCECPGAP2 →+0.382+2.425.008.00231
UCECCOX15 →+0.454+3.467.002.00231
UCECINTS4 →+0.386+2.931.001<.00131
UCECTMEM138 →+0.250+3.346.009.00531
UCECCHEK1 →+0.795+2.436<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,919 associations by consensus.

LINC02672 by CETN2 expression — SKCM

Box plot of LINC02672 in CETN2-low vs CETN2-high samples in SKCM.

Explore this box plot interactively →

Exploration