CETN2

Across TCGA pan-cancer cohorts, CETN2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CETN2 data layer compared with 2 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher CETN2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CETN2 expression acts as an unfavorable survival marker, although some lineages such as UVM and CESC show a favorable association.

UVM, KICH, and CESC are the cancer types where CETN2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	II,III,IV	0.844	0.445	<.001	64	view →
KICH	OS	Tertile	All	0.707	1.000	.005	57	view →
CESC	OS	Median	All	0.759	0.421	<.001	36	view →
LGG	OS	Tertile	All	0.723	0.894	<.001	35	view →
OV	DFS	Median	III,IV	0.409	0.332	.011	34	view →
HNSC	DFS	Median	III,IV	0.518	0.659	.010	26	view →
SCLC	DFS	Tertile	All	0.603	1.000	.012	26	view →
ACC	OS	Median	II,III,IV	0.771	0.927	.007	24	view →
LIHC	OS	Quartile	All	0.719	0.857	.001	22	view →
THCA	DFS	Median	All	0.968	0.900	.004	18	view →
UCEC	OS	Tertile	III,IV	0.901	0.747	.014	18	view →
LUSC	OS	Quartile	All	0.883	0.664	.024	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CETN2–UVM (OS)

Open the UVM breakdown →