CETN1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CETN1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CETN1-associated genes across cancer lineages are WFDC6 and ACTRT2. Each is linked with CETN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CETN1-to-partner and partner-to-CETN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC6 grouped by CETN1-low versus CETN1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CETN1→partner) and Y-score (partner→CETN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADWFDC6 →+0.070+4.887<.001.00931
LUNG_SCLCACTRT2 →+0.013+5.643<.001.00231
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

WFDC6 by CETN1 expression — LUNG_NSCLC_LUAD

Box plot of WFDC6 in CETN1-low vs CETN1-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration