CETN1

Across TCGA pan-cancer cohorts, CETN1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CETN1 data layer compared with 4 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher CETN1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CETN1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

UVM, LIHC, and UCS are the cancer types where CETN1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.104	0.856	<.001	63	view →
LIHC	OS	Tertile	All	0.501	0.713	<.001	57	view →
UCS	DFS	Tertile	All	0.797	0.359	.011	48	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	45	view →
LUAD	OS	Tertile	All	0.525	0.792	.021	30	view →
COAD	OS	Tertile	All	0.457	0.802	.020	27	view →
LGG	DFS	Tertile	All	0.198	0.476	<.001	27	view →
THCA	OS	Tertile	All	0.240	0.931	.010	21	view →
BLCA	OS	Tertile	IV	0.260	0.605	.014	18	view →
SKCM	DFS	Tertile	II,III,IV	0.731	0.267	.019	15	view →
UCEC	OS	Tertile	III,IV	0.333	0.621	.045	12	view →
TGCT	DFS	Tertile	All	0.923	0.724	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CETN1–UVM (OS)

Open the UVM breakdown →