CERS6

Across TCGA cell cohorts, CERS6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,055 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CERS6-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Copper ion export, and Post-Golgi vesicle-mediated transport. Each is linked with CERS6 in more than 11 cancer types. Because this analysis shows association rather than direction, both CERS6-to-partner and partner-to-CERS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by CERS6-low versus CERS6-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CERS6→partner) and Y-score (partner→CERS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of nucleotide-excision repair →	+0.097	+0.748	<.001	<.001	3	12
STOMACH	Copper ion export →	-0.153	-1.417	<.001	<.001	3	10
BREAST	Post-Golgi vesicle-mediated transport →	+0.050	+0.759	.001	<.001	3	9
BLOOD_Leukemia	Protein localization to cytoplasmic stress granule →	+0.120	+1.031	<.001	<.001	3	9
OVARY	Regulation of termination of RNA polymerase II transcription →	+0.082	+0.553	.002	.003	3	8
OVARY	Regulation of termination of DNA-templated transcription →	+0.082	+0.553	.002	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,055 associations by consensus.

Regulation of nucleotide-excision repair by CERS6 expression — OVARY

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