CERS3-AS1

Across TCGA pan-cancer cohorts, CERS3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CERS3-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CERS3-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CERS3-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, READ, and DLBC are the cancer types where CERS3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.624	0.280	<.001	66	view →
READ	OS	Tertile	All	0.235	0.856	<.001	63	view →
DLBC	OS	Tertile	All	0.447	0.956	.004	57	view →
HNSC	DFS	Tertile	All	0.455	0.271	<.001	51	view →
ESCA	OS	Quartile	All	1.000	0.343	.009	38	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	36	view →
STAD	OS	Median	II,III,IV	0.509	0.289	.009	28	view →
UCS	DFS	Tertile	III,IV	0.569	0.132	.013	26	view →
LUSC	OS	Median	II,III,IV	0.811	0.646	.005	23	view →
ACC	DFS	Median	All	0.744	0.505	.016	19	view →
MESO	OS	Median	III,IV	0.539	0.298	.005	17	view →
BLCA	OS	Median	All	0.681	0.756	.021	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CERS3-AS1–LUAD (OS)

Open the LUAD breakdown →