CERS3-AS1

Across TCGA pan-cancer cohorts, CERS3-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CERS3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CERS3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CERS3-AS1 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

KIRC, UCEC, and BRCA are the cancer types where CERS3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CERS3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.518	<.001	11	view →
UCEC	All	III,IV	−1.617	<.001	6	view →
BRCA	All	III,IV	−1.156	<.001	6	view →
LUSC	Female	All	+1.057	<.001	6	view →
KIRP	Male	All	+0.588	<.001	6	view →
LUAD	Male	All	−0.399	<.001	6	view →
COAD	All	All	−0.167	<.001	5	view →
STAD	All	II,III,IV	−0.694	.001	4	view →
ESCA	All	II,III,IV	−1.845	.035	2	view →
BLCA	Female	All	−0.897	.018	2	view →
PRAD	All	All	−0.841	<.001	2	view →
READ	All	All	−0.300	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CERS3-AS1–KIRC

Open the KIRC breakdown →