CERS2

Across TCGA patient cohorts, CERS2 mutation is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CERS2-associated genes across cancer lineages are OR56A7P, RNY1P1, and MIR3194. Each is linked with CERS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CERS2-to-partner and partner-to-CERS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A7P grouped by CERS2-low versus CERS2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CERS2→partner) and Y-score (partner→CERS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR56A7P →	+0.068	+5.038	<.001	.009	3	2
UCEC	RNY1P1 →	+0.230	+3.113	<.001	.006	3	2
PRAD	MIR3194 →	+0.532	+6.206	<.001	.001	3	2
SKCM	LINC02000 →	+0.107	+5.436	<.001	.005	3	1
SKCM	RN7SL870P →	+0.139	+5.097	<.001	.008	3	1
SKCM	WSPAR →	+0.065	+5.867	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

OR56A7P by CERS2 expression — BLCA

Explore this box plot interactively →