CERK

Across TCGA patient cohorts, CERK RNA expression is significantly associated with the protein abundance of many other proteins, with 14,752 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CERK-associated proteins across cancer lineages are RNF213, DTX3L, and TAP1. Each is linked with CERK in more than 4 cancer types. Because this analysis shows association rather than direction, both CERK-to-partner and partner-to-CERK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CERK versus RNF213 in LUAD, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CERK→partner) and Y-score (partner→CERK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNF213 →	-0.429	-0.414	<.001	.001	3	5
HNSC	DTX3L →	-0.329	-0.603	<.001	<.001	3	5
CCRCC	TAP1 →	-0.463	-0.431	<.001	<.001	3	5
GBM	TAPBP →	-0.495	-0.321	.001	.006	3	5
LSCC	TCF20 →	+0.282	+0.548	<.001	<.001	3	5
GBM	TNRC6B →	+0.224	+0.416	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,752 associations by consensus.

CERK vs RNF213 — LUAD

Explore this scatter interactively →