CERK

Across TCGA patient cohorts, CERK protein abundance is significantly associated with the RNA expression of many other genes, with 7,322 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CERK-associated genes across cancer lineages are SDHDP1, SPP1, and KCNK1. Each is linked with CERK in more than 1 cancer types. Because this analysis shows association rather than direction, both CERK-to-partner and partner-to-CERK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CERK versus SDHDP1 in BRCA, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CERK→partner) and Y-score (partner→CERK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SDHDP1 →	+0.465	+0.567	.007	.003	3	2
LUAD	SPP1 →	-1.844	-0.441	.002	<.001	3	2
LUAD	KCNK1 →	+2.109	+0.592	.008	.003	3	2
LSCC	ZNF367 →	-1.094	-0.582	<.001	.004	3	2
LUAD	GPR27 →	+0.980	+0.481	.001	.001	3	2
LSCC	FBXO16 →	+0.744	+0.422	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,322 associations by consensus.

CERK vs SDHDP1 — BRCA

Explore this scatter interactively →