CER1

Across TCGA patient cohorts, CER1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,844 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CER1-associated GO terms across cancer lineages are Regulation of microtubule polymerization, Obsolete regulation of nodal signaling pathway involved in determination of left/right asymmetry, and Nucleobase-containing compound transport. Each is linked with CER1 in more than 16 cancer types. Because this analysis shows association rather than direction, both CER1-to-partner and partner-to-CER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule polymerization grouped by CER1-low versus CER1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CER1→partner) and Y-score (partner→CER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of microtubule polymerization →	+0.033	+0.174	<.001	.001	3	17
SKCM	Obsolete regulation of nodal signaling pathway involved in determination of left/right asymmetry →	-0.090	-0.137	<.001	<.001	3	16
STAD	Nucleobase-containing compound transport →	+0.050	+0.240	<.001	.001	3	16
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.062	+0.271	<.001	.007	3	16
STAD	Golgi organization →	+0.050	+0.225	<.001	.003	3	15
STAD	Obsolete histone methylation →	+0.060	+0.256	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,844 associations by consensus.

Regulation of microtubule polymerization by CER1 expression — STAD

Explore this box plot interactively →