CEP97

Across TCGA patient cohorts, CEP97 mutation is significantly associated with the RNA expression of many other genes, with 3,913 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP97-associated genes across cancer lineages are MIR6877, TRGJP2, and CDADC1. Each is linked with CEP97 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP97-to-partner and partner-to-CEP97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6877 grouped by CEP97-low versus CEP97-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP97→partner) and Y-score (partner→CEP97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	MIR6877 →	+0.545	+4.680	.001	.004	3	3
COAD	TRGJP2 →	+1.387	+4.811	<.001	<.001	3	3
UCEC	CDADC1 →	+0.401	+2.354	<.001	<.001	3	3
UCEC	PCBD2 →	+0.289	+2.000	.001	.001	3	3
UCEC	DIAPH3 →	+0.754	+2.400	<.001	<.001	3	3
UCEC	ATG12 →	+0.425	+2.243	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,913 associations by consensus.

MIR6877 by CEP97 expression — LGG

Explore this box plot interactively →