CEP97

Across TCGA patient cohorts, CEP97 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP97-associated genes across cancer lineages are NDRG1_pT346, 4E-BP1, and eIF4E. Each is linked with CEP97 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP97-to-partner and partner-to-CEP97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDRG1_pT346 grouped by CEP97-low versus CEP97-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP97→partner) and Y-score (partner→CEP97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDRG1_pT346 →	-0.394	-1.584	.025	.019	3	2
UCEC	4E-BP1 →	+0.216	+3.321	.026	.009	3	2
UCEC	eIF4E →	+0.160	+3.013	.035	.018	3	1
UCEC	eIF4G →	+0.249	+1.807	.025	.025	3	1
UCEC	INPP4B →	-0.247	-1.906	.033	.015	3	1
UCEC	Ku80 →	+0.191	+1.495	.025	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

NDRG1_pT346 by CEP97 expression — UCEC

Explore this box plot interactively →