CEP89

Across TCGA patient cohorts, CEP89 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,958 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CEP89-associated proteins across cancer lineages are SAE1, UBA2, and CHD4. Each is linked with CEP89 in more than 6 cancer types. Because this analysis shows association rather than direction, both CEP89-to-partner and partner-to-CEP89 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEP89 versus SAE1 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP89→partner) and Y-score (partner→CEP89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SAE1 →	+0.300	+0.518	<.001	.001	3	7
BRCA	UBA2 →	+0.351	+0.566	<.001	<.001	3	7
GBM	CHD4 →	+0.356	+0.373	.001	.005	3	6
HNSC	DHX35 →	+0.304	+0.791	<.001	<.001	3	6
OV	GPATCH1 →	+0.477	+0.683	.002	.007	3	6
BRCA	TBCB →	+0.419	+0.648	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,958 associations by consensus.

CEP89 vs SAE1 — BRCA

Explore this scatter interactively →