CEP89

Across TCGA patient cohorts, CEP89 protein abundance is significantly associated with the RNA expression of many other genes, with 9,736 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CEP89-associated genes across cancer lineages are WDR86-AS1, CFAP300, and FHAD1. Each is linked with CEP89 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP89-to-partner and partner-to-CEP89 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEP89 versus WDR86-AS1 in UCEC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP89→partner) and Y-score (partner→CEP89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR86-AS1 →	+1.880	+0.236	<.001	<.001	3	3
UCEC	CFAP300 →	+1.251	+0.237	.001	.002	3	3
UCEC	FHAD1 →	+1.044	+0.241	<.001	<.001	3	3
PDAC	RUBCNL →	+0.523	+0.625	.007	.002	3	2
PDAC	FLT1 →	+0.695	+0.537	<.001	.006	3	2
PDAC	BFAR →	-0.450	-0.630	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,736 associations by consensus.

CEP89 vs WDR86-AS1 — UCEC

Explore this scatter interactively →