CEP85L

Across TCGA patient cohorts, CEP85L mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP85L-associated genes across cancer lineages are ASNS, eIF4E, and PCNA. Each is linked with CEP85L in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP85L-to-partner and partner-to-CEP85L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by CEP85L-low versus CEP85L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP85L→partner) and Y-score (partner→CEP85L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.420	+1.765	<.001	.013	3	3
UCEC	eIF4E →	+0.219	+2.643	.001	<.001	2	3
STAD	PCNA →	+0.319	+3.000	.032	.036	3	2
STAD	Tuberin_pT1462 →	-0.217	-3.000	.030	.036	3	2
COAD	Shc_pY317 →	-0.193	-3.305	.004	.009	3	2
UCEC	ATM →	-0.533	-1.938	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

ASNS by CEP85L expression — UCEC

Explore this box plot interactively →