CEP83-DT

Across TCGA pan-cancer cohorts, CEP83-DT RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CEP83-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CEP83-DT RNA is repressed in tumor relative to normal tissue. In most cancer types CEP83-DT is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, HNSC, and THCA are the cancer types where CEP83-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEP83-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.522	<.001	10	view →
HNSC	Male	III,IV	+0.334	<.001	9	view →
THCA	Male	All	−0.425	<.001	8	view →
LIHC	Female	II,III,IV	+0.210	<.001	8	view →
KICH	Female	All	−1.077	<.001	7	view →
BLCA	All	All	+0.526	.002	6	view →
STAD	All	II,III,IV	+0.250	.004	6	view →
LUSC	All	All	+0.386	<.001	5	view →
LUAD	All	All	+0.269	<.001	3	view →
CHOL	All	All	+0.335	.005	2	view →
COAD	All	II,III,IV	+0.179	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CEP83-DT–KIRC

Open the KIRC breakdown →