CEP70

Across TCGA cell cohorts, CEP70 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP70-associated genes across cancer lineages are GSK2801, Quizartinib, and Masitinib. Each is linked with CEP70 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP70-to-partner and partner-to-CEP70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2801 grouped by CEP70-low versus CEP70-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP70→partner) and Y-score (partner→CEP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2801 →	+0.360	+2.649	.023	.046	3	1
LARGE_INTESTINE	Quizartinib →	+0.342	+2.652	.034	.045	3	1
LARGE_INTESTINE	Masitinib →	+0.505	+2.652	.018	.045	3	1
LARGE_INTESTINE	T0901317 →	+0.353	+2.722	.009	.040	3	1
LARGE_INTESTINE	IWP-2 →	+0.278	+2.893	.037	.034	2	1
LARGE_INTESTINE	SGC-CBP30 →	+0.324	+2.649	.021	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GSK2801 by CEP70 expression — LARGE_INTESTINE

Explore this box plot interactively →