CEP70

Across TCGA pan-cancer cohorts, CEP70 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CEP70 data layer compared with 5 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CEP70 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CEP70 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, ACC, and SKCM are the cancer types where CEP70 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.840	0.670	.001	63	view →
ACC	DFS	Median	All	0.271	0.617	<.001	53	view →
SKCM	OS	Quartile	II,III,IV	0.929	0.788	<.001	44	view →
READ	DFS	Quartile	II,III,IV	0.823	0.244	<.001	41	view →
MESO	OS	Median	All	0.282	0.469	.004	37	view →
PAAD	OS	Quartile	All	0.224	0.638	.001	36	view →
LGG	DFS	Median	All	0.671	0.805	<.001	26	view →
CESC	OS	Tertile	All	0.895	0.726	.002	18	view →
THYM	OS	Median	II,III,IV	0.941	0.705	.006	13	view →
UCS	DFS	Median	IV	0.811	0.514	.039	12	view →
STAD	OS	Median	All	0.645	0.426	.018	9	view →
LIHC	OS	Median	III,IV	0.849	0.532	.003	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CEP70–LUAD (OS)

Open the LUAD breakdown →