CEP68

Across TCGA cell cohorts, CEP68 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CEP68-associated genes across cancer lineages are ETDC, GUCA2A, and IAPP. Each is linked with CEP68 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP68-to-partner and partner-to-CEP68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETDC grouped by CEP68-low versus CEP68-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP68→partner) and Y-score (partner→CEP68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ETDC →	+0.523	+5.228	<.001	.005	3	1
SKIN	GUCA2A →	+0.083	+4.273	<.001	.006	3	1
OVARY	IAPP →	+0.964	+3.657	<.001	.009	3	1
LUNG_SCLC	TRIML1 →	+0.179	+4.269	<.001	.005	3	1
LUNG_SCLC	KRTAP9-1 →	+0.168	+4.044	<.001	.009	3	1
BREAST	LCN9 →	+0.079	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ETDC by CEP68 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →