CEP55

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CEP55 mutation is significantly associated with the RNA expression of many other genes, with 3,001 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP55-associated genes across cancer lineages are LINC01817, IQCF2, and MIR670. Each is linked with CEP55 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP55-to-partner and partner-to-CEP55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01817 grouped by CEP55-low versus CEP55-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP55→partner) and Y-score (partner→CEP55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01817 →+0.057+4.469<.001.00632
LUADIQCF2 →+0.261+4.984<.001.00532
LUADMIR670 →+0.359+5.315<.001.00332
LUADPPP1R2P10 →+1.084+4.218<.001.00932
LUADSNORA3C →+0.632+5.087<.001.00432
LUADPPP1R2P5 →+0.034+5.315.004.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,001 associations by consensus.

LINC01817 by CEP55 expression — SKCM

Box plot of LINC01817 in CEP55-low vs CEP55-high samples in SKCM.

Explore this box plot interactively →

Exploration