CEP55

Across TCGA pan-cancer cohorts, CEP55 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of CEP55’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CEP55 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEP55 is over-expressed in tumor.

HNSC, KIRC, and LUAD are the cancer types where CEP55 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEP55 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+2.738	<.001	12	view →
KIRC	Male	IV	+1.852	<.001	12	view →
LUAD	Male	III,IV	+3.871	<.001	11	view →
BLCA	All	IV	+3.137	<.001	11	view →
KIRP	Male	III,IV	+2.471	<.001	11	view →
COAD	Male	All	+1.712	<.001	11	view →
LUSC	Male	III,IV	+4.059	<.001	9	view →
STAD	Female	All	+2.992	<.001	9	view →
UCEC	All	III,IV	+4.321	<.001	8	view →
LIHC	Female	II,III,IV	+1.484	<.001	8	view →
THCA	All	III,IV	+0.783	<.001	8	view →
READ	All	All	+1.431	<.001	7	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

CEP55–HNSC

Open the HNSC breakdown →