CEP44

Across TCGA cell cohorts, CEP44 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP44-associated genes across cancer lineages are IFNG, OR1N1, and TBPL2. Each is linked with CEP44 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP44-to-partner and partner-to-CEP44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNG grouped by CEP44-low versus CEP44-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP44→partner) and Y-score (partner→CEP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	IFNG →	+0.016	+4.437	<.001	.004	3	1
SKIN	OR1N1 →	+0.020	+4.437	<.001	.004	3	1
SKIN	TBPL2 →	+0.042	+3.684	<.001	.006	3	1
SKIN	TRIM49C →	+0.038	+3.920	.001	.005	3	1
LARGE_INTESTINE	SCGB2A1 →	+0.427	+3.392	.003	.006	3	1
LARGE_INTESTINE	ANO5 →	+0.584	+3.541	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

IFNG by CEP44 expression — SKIN

Explore this box plot interactively →