CEP250

Across TCGA patient cohorts, CEP250 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,578 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CEP250-associated proteins across cancer lineages are THOC6, THOC1, and THOC2. Each is linked with CEP250 in more than 6 cancer types. Because this analysis shows association rather than direction, both CEP250-to-partner and partner-to-CEP250 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEP250 versus THOC6 in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP250→partner) and Y-score (partner→CEP250) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THOC6 →	+0.266	+0.565	<.001	<.001	3	7
LSCC	THOC1 →	+0.297	+0.656	<.001	<.001	3	6
BRCA	THOC2 →	+0.376	+0.682	<.001	<.001	3	6
BRCA	ADNP →	+0.347	+0.651	<.001	<.001	3	6
GBM	CTNNBL1 →	+0.362	+0.407	<.001	<.001	3	6
LSCC	CSE1L →	+0.353	+0.668	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,578 associations by consensus.

CEP250 vs THOC6 — LSCC

Explore this scatter interactively →