CEP170

Across TCGA cell cohorts, CEP170 mutation is significantly associated with the RNA expression of many other genes, with 1,543 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP170-associated genes across cancer lineages are TRAT1, VWC2L, and PGPEP1L. Each is linked with CEP170 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP170-to-partner and partner-to-CEP170 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAT1 grouped by CEP170-low versus CEP170-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP170→partner) and Y-score (partner→CEP170) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TRAT1 →	+2.780	+3.491	<.001	.009	3	3
LUNG_NSCLC_LUAD	VWC2L →	+0.013	+2.465	<.001	.009	3	2
BLOOD_Leukemia	PGPEP1L →	+1.151	+3.032	<.001	.007	3	2
STOMACH	ASZ1 →	+0.123	+2.080	.008	.006	3	2
BLOOD_Leukemia	GPR151 →	+0.029	+3.853	.005	.002	3	2
BLOOD_Leukemia	OR4E1 →	+0.305	+3.269	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,543 associations by consensus.

TRAT1 by CEP170 expression — BLOOD_Leukemia

Explore this box plot interactively →