CEP135

Across TCGA pan-cancer cohorts, CEP135 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CEP135 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CEP135 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CEP135 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where CEP135 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.776	0.354	<.001	42	view →
HNSC	OS	Median	All	0.924	0.788	.003	24	view →
LUAD	OS	Quartile	III,IV	0.723	1.000	.031	5	view →
PDAC	DFS	Tertile	IV	0.752	0.203	.024	3	view →
UCEC	DFS	Median	II,III,IV	0.826	1.000	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CEP135–CCRCC (DFS)

Open the CCRCC breakdown →