CEP135

Across TCGA cell cohorts, CEP135 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,919 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEP135-associated GO terms across cancer lineages are Double-strand break repair via nonhomologous end joining, Centrosome cycle, and Centriole replication. Each is linked with CEP135 in more than 19 cancer types. Because this analysis shows association rather than direction, both CEP135-to-partner and partner-to-CEP135 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via nonhomologous end joining grouped by CEP135-low versus CEP135-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP135→partner) and Y-score (partner→CEP135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.060	+0.853	<.001	.002	3	20
OESOPHAGUS	Centrosome cycle →	+0.095	+0.934	<.001	<.001	3	20
KIDNEY	Centriole replication →	+0.128	+1.022	<.001	<.001	3	20
KIDNEY	Centriole assembly →	+0.111	+0.865	<.001	<.001	3	20
OESOPHAGUS	Microtubule organizing center organization →	+0.087	+0.934	<.001	<.001	3	20
OESOPHAGUS	Nuclear chromosome segregation →	+0.122	+0.773	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,919 associations by consensus.

Double-strand break repair via nonhomologous end joining by CEP135 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →