CEP135

Across TCGA cell cohorts, CEP135 mutation is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP135-associated genes across cancer lineages are OR7A10, OR1E2, and GPR119. Each is linked with CEP135 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP135-to-partner and partner-to-CEP135 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7A10 grouped by CEP135-low versus CEP135-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP135→partner) and Y-score (partner→CEP135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR7A10 →	+0.011	+4.022	<.001	.006	3	1
SKIN	OR1E2 →	+0.046	+4.022	<.001	.006	3	1
SKIN	GPR119 →	+0.019	+3.196	.002	.007	3	1
SKIN	KRTAP15-1 →	+0.025	+4.022	<.001	.006	3	1
LARGE_INTESTINE	SAMM50 →	+0.598	+3.234	<.001	.004	3	1
LARGE_INTESTINE	DESI1 →	+0.506	+3.169	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

OR7A10 by CEP135 expression — SKIN

Explore this box plot interactively →