CEP128

Across TCGA patient cohorts, CEP128 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP128-associated genes across cancer lineages are MEK1, Rictor_pT1135, and Notch1. Each is linked with CEP128 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP128-to-partner and partner-to-CEP128 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by CEP128-low versus CEP128-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP128→partner) and Y-score (partner→CEP128) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.379	+1.700	<.001	.001	3	3
SKCM	Rictor_pT1135 →	-0.150	-1.982	.029	.031	3	3
UCEC	Notch1 →	+0.126	+1.676	.001	.005	3	3
UCEC	ASNS →	+0.269	+1.280	.007	.049	3	3
UCEC	Cyclin-B1 →	+0.636	+1.874	<.001	<.001	3	3
STAD	FoxM1 →	+0.304	+3.031	.013	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

MEK1 by CEP128 expression — UCEC

Explore this box plot interactively →