CEP128

Across TCGA pan-cancer cohorts, CEP128 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CEP128 data layer compared with 8 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CEP128 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CEP128 expression acts as an unfavorable survival marker, although some lineages such as SCLC and UCS show a favorable association.

ACC, KICH, and MESO are the cancer types where CEP128 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.354	0.828	<.001	112	view →
KICH	DFS	Tertile	II,III,IV	0.403	0.899	.001	74	view →
MESO	DFS	Quartile	All	0.275	0.602	<.001	69	view →
LGG	OS	Median	All	0.741	0.882	<.001	48	view →
SCLC	OS	Quartile	II,III,IV	0.710	0.240	.001	46	view →
UCS	OS	Median	IV	0.817	0.302	.002	36	view →
LUSC	DFS	Tertile	III,IV	0.318	1.000	.006	33	view →
SARC	OS	Median	All	0.449	0.715	.003	29	view →
BRCA	OS	Quartile	IV	0.679	0.227	.013	27	view →
KIRP	OS	Tertile	All	0.578	0.765	.004	25	view →
SKCM	OS	Quartile	All	0.823	0.703	.006	25	view →
ESCA	OS	Quartile	II,III,IV	0.693	0.320	<.001	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CEP128–ACC (OS)

Open the ACC breakdown →