CEP128

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CEP128 mutation is significantly associated with the RNA expression of many other genes, with 449 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP128-associated genes across cancer lineages are OR9A2, GTSF1L, and APTX. Each is linked with CEP128 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP128-to-partner and partner-to-CEP128 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9A2 grouped by CEP128-low versus CEP128-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP128→partner) and Y-score (partner→CEP128) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaOR9A2 →+0.022+5.209<.001.00533
LUNG_NSCLC_LUADGTSF1L →+0.026+2.637<.001.00733
LARGE_INTESTINEAPTX →+0.313+3.321.008.00332
LARGE_INTESTINEANXA7 →+0.473+2.502.002.00532
LARGE_INTESTINEUSP43 →+0.667+2.502.004.00532
LARGE_INTESTINEFRRS1 →+0.988+3.628<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 449 associations by consensus.

OR9A2 by CEP128 expression — BLOOD_Lymphoma

Box plot of OR9A2 in CEP128-low vs CEP128-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration