CEP128

Across TCGA cell cohorts, CEP128 mutation is significantly associated with the mutation status of many other genes, with 3,321 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP128-associated genes across cancer lineages are ZNF536, PCDH7, and KIAA1549L. Each is linked with CEP128 in more than 4 cancer types. Because this analysis shows association rather than direction, both CEP128-to-partner and partner-to-CEP128 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF536 grouped by CEP128-low versus CEP128-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP128→partner) and Y-score (partner→CEP128) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZNF536 →	+3.169	+4.601	.003	.003	1	5
SKIN	PCDH7 →	+3.548	+3.210	.001	.001	1	5
BLOOD_Leukemia	KIAA1549L →	+2.499	+2.697	.002	.002	1	5
BLOOD_Leukemia	HYDIN →	+3.125	+3.343	<.001	<.001	1	5
SOFT_TISSUE	GRIK2 →	+4.502	+5.066	.007	.007	1	5
LUNG_NSCLC_LUAD	SCN2A →	+2.230	+2.664	.005	.005	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,321 associations by consensus.

ZNF536 by CEP128 expression — BLOOD_Lymphoma

Explore this box plot interactively →