Across TCGA patient cohorts, CENPW protein abundance is significantly associated with the RNA expression of many other genes, with 109 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CENPW-associated genes across cancer lineages are KCNN4, H2AZ2, and UHRF1BP1L. Each is linked with CENPW in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPW-to-partner and partner-to-CENPW results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPW→partner) and Y-score (partner→CENPW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KCNN4 →	-1.914	-0.790	<.001	.004	3	1
LUAD	H2AZ2 →	-0.620	-0.790	.005	.004	3	1
LUAD	UHRF1BP1L →	-0.474	-0.790	.001	.004	3	1
LUAD	QKI →	-0.513	-0.843	<.001	.001	3	1
LUAD	CEP72 →	-1.018	-0.775	.005	.006	3	1
LUAD	TENT4A →	-0.632	-0.790	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 109 associations by consensus.

Exploration

CENPW survival (RNA) · tumor vs normal (RNA) · all CENPW data types